Although common among Neonatal Intensive Care Units, multiples births are randomized inconsistently within trials, which can impact enrollment, analytical approach and trial outcomes. It is not known ...

Mendelian randomization is not affected by the confounding inherent in observational studies but it does rely on several assumptions, which can be hard to test Mendelian randomization can provide a ...

While randomization is required by regulatory bodies, it is up to the sponsor on how to conduct it. Developing a clinical trial’s effective monitoring plan can be overwhelming. The FDA acknowledges ...

Although numerous Mendelian randomization studies on risk factors have been conducted in male medicine, a systematic synthesis of these findings is still lacking. This review searched relevant ...

Several studies have suggested that N6‐methyladenosine (m6A) plays an essential role in cardiovascular disease, but the causality of m6A on ischemic heart disease (IHD) remains unknown. Therefore, ...

Researchers argue that, in some situations where machine-learning models are used to allocate scarce resources or opportunities, randomizing decisions in a structured way may lead to fairer outcomes.