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#rolandoasisten 273. The Handshake Problem. In a room of 50 people, how many different handshakes are possible? This problems is presented in the context of handshakes, but this type of math problem provides a thinking model on how to analyze mathematically communication and other network characteristics such as the flow of gossip and information in certain social groups, the propagation of data packets in local area network, or even the use of neural network that tried to mimic the human brain